To fight diarrhea

Lactéol® is an effective treatment for diarrhea, given in addition to rehydration
and/or dietary measures, in both children and adults.1

Bacterial strains are proprietary to Adare Biome, they are registered and stored at the Pasteur Institute, Paris

Lactobacillus LB, a natural and
powerful combination to maximize anti - diarrheal activity1

1 capsule or 1 sachet contains:

5 or 10 billion heat - treated Lactobacillus LB* from human origin

Culture medium actives from bacterial metabolic activity

Lactéol® is produced by an optimized and proprietary pharmaceutical GMP manufacturing process


Heat - treatment

Freeze - drying

LEARN MORE: Adare Biome (ECHO process)

*L. fermentum & L. delbrueckii

Lactéol®, a powerful combination of actions to fight diarrhea

  • Microbiota friendly effect: reinforcement of the intestinal microbiota through inhibition of enterovirulent bacteria and support of the natural bacteria of the microbiota.1,3
  • Stimulates natural defenses: enhancement of non - specific immune - stimulation of mucosal IgA production.1,3
  • Antagonistic or regulatory activity towards viruses and bacteria: neutralization and inhibition of pathogen - activated cell signalling pathways. 4
  • Adhesion to the mucosa: inhibition of the attachment of pathogens and their internalisation. 3-5
  • Bacteriostatic effect: blockage of the growth of enterovirulent bacteria as a result of strain - specific production of antibacterial compounds. 5

Lactéol®, well established clinical efficacy for multiple types of diarrhea

Lactéol® has demonstrated efficacy in randomised controlled studies in children and adults, it shortens the duration of diarrhea and improves stool consistency.

The activity of Lactéol® is the result of a combination of heat - treated bacteria and a culture medium containing active bacterial metabolites. Lactéol® has demonstrated clinical efficacy in diarrhea of various types:

• Non - Rotavirus diarrhea in children8
• Acute, Rotavirus - positive diarrhea in children2
• Mild, Acute diarrhea in children9
• Acute diarrhea in adults6
• Antibiotic associated diarrhea in adults7
• Chronic diarrhea in adults3
• Irritable Bowel Syndrome (IBS) in adults10

Learn more

Lactéol®, suitable
for the whole family

Dosage forms for the whole family1

Powder sachets for oral suspension for all ages
Capsules for ages 6 and older

Click on the product of your choice to learn how to take Lactéol®?1

1 sachet of Lactéol® 340 mg contains:
• 10 billion Lactobacillus LB
• culture medium with actives

Dosing: 1 or 2 sachets per day according to the severity of the condition. The dosage may be increased to 3 sachets on the 1st
day of treatment.

Flavour: orange-banana

1 capsule of Lactéol® 340 mg contains:
• 10 billion Lactobacillus LB
• culture medium with actives

Dosing: 1 or 2 capsules per day according to the severity of the condition. The dosage may be increased to 3 capsules on the 1st day of treatment.

1 capsule of Lactéol® 170 mg contains:
• 5 billion Lactobacillus LB
• culture medium with actives

Dosing: 2 or 4 capsules per day according to the severity of the condition. The dosage may be increased to 6 capsules on the 1st day of treatment.

Good safety profile1

Well tolerated by all ages, without serious side - effects**. Lactéol® has been heat  -  treated and it can be administered to the very youngest and the elderly.

Product registration status, approved indication and labeling, product availability, packaging information and design and prescription information are country dependent and vary from a country to another. For your country specific information, refer to the local product label or to the local health authority database.

**Hypersensitivity reactions and urticaria have been reported as part of the pharmacovigilance programme.

Why recommend Lactéol® to fight against diarrhea ?

Well controlled clinical trials demonstrate that Lactéol® shortens the duration of diarrhea and improves stool consistency.
A unique postbiotic composition: heat  - treated Lactobacillus LB with culture medium actives.
Lactéol® is recommended by the European Society for Paediatric Gastroenterology, Hepathology and Nutrition Guidelines (ESPGHAN) treatment of diarrhea.
Lactéol® can be used by all members of the family, it is well tolerated even in very young children.
No interaction with the use of other systemic medications have been reported.
Drug forms for the whole family sachets or capsules.
Stable at room temperature, making it easy to transport and store.

# Bacterial species naturally present in the human microbiota

  1. Lactéol®. Summary of Product Characteristics. Houdan, France: Adare Pharmaceuticals; 2017.
  2. Simakachorn N, Pichaipat V, Rithipornpaisarn P, Kongkaew C, Tongpradit P, Varavithya W. Clinical evaluation of the addition of lyophilized, heat-killed Lactobacillus acidophilus LB to oral rehydration therapy in the treatment of acute diarrhea in children. J Pediatr Gastroenterol Nutr 2000;30:68-72.
  3. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther 2003;20:253-60.
  4. Liévin-Le Moal V. A gastrointestinal anti-infectious biotherapeutic agent: the heat-treated Lactobacillus LB. Therap Adv Gastroenterol. 2016;9(1):57-75.
  5. Liévin-Le Moal V, Servin AL. Anti-infective activities of Lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents. Clin Microbiol Rev 2014;27(2):167-99.
  6. Salgado AJ, Garcia Jara JA. Treatment with Lactéol® Fort of adults suffering from acute diarrhea in Mexico. Rev Hosp Mujer 1993;2:61-3.
  7. Yap Soo Kor JA, Gwee Kok A, Chen ZA, Tai Bee Choo A, Wong Mee L. Lacteol® Fort treatment reduces antibiotic associated diarrhea. Singapore Fam Physician 2010;34:46-9.
  8. Liévin-Le Moal V, Sarrazin-Davila LE, Servin AL. An experimental study and a randomized, double-blind, placebo-controlled clinical trial to evaluate the antisecretory activity of Lactobacillus acidophilus strain LB against nonrotavirus diarrhea. Pediatrics 2007;120:e795-803.
  9. Salazar-Lindo E, Figueroa-Quintanilla D, Caciano MI, Reto-Valiente V, Chauviere G, Colin P. Effectiveness and safety of Lactobacillus LB in the treatment of mild acute diarrhea in children. J Pediatr Gastroenterol Nutr 2007;44:571-6.
  10. Tarrerias AL, Costil V, Vicari F, et al. The effect of inactivated Lactobacillus LB fermented culture medium on symptom severity: observational investigation in 297 patients with diarrhea-predominant irritable bowel syndrome. Dig Dis 2011;29:588-91.
  11. Martin R., Langela P. Emerging Health Concepts in the Probiotics field: Streaming the definitions. Frontiers in Microbiology. 2019; 10, 1047.
  12. Guarino A, Ashkenazi S, Gendrel D, Lo Vecchio A, Shamir R, Szajewska H. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition/European Society for Pediatric Infectious Diseases evidence-based guidelines for the management of acute gastroenteritis in children in Europe: update 2014. J Pediatr Gastroenterol Nutr 2014;59:132-52.
  13. Lactéol®. Summary of Product Characteristics. Italy: Adare Pharmaceuticals.

Lactéol® - Frequently Asked Question

  • Is Lactéol® a probiotic?
  • How can Lactéol® be effective when it has been inactivated?
  • When should I prescribe or recommended Lactéol®?
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